Has any of you regret not having children?

[amg55]

My dad passed away just a couple of weeks ago. He had been ill for a few years and during that time, he had his kids and grand children around him. I think that kept him going for a bit longer. I've just turned 52 and for the first time I ask myself if it's too late to start a family now or will it make any difference in 10 - 20 years time. Will the children even care about us when the time comes. I'd be most interested to hear some of your thoughts.