A New Correlation on Opioid Addiction

[BristolCavendish]

Some of you may have already read (or heard) about these findings. Medical researchers at Dartmouth and the University of Michigan have found that there is a direct connection between opioid addiction and depression/anxiety disorders. While the total % may appear small (in certain respects), 19% of the 3.8M annually prescribed vicodin, percoset et al tend to develop addiction issues based on their interpretation of pain. In other words, while a 'normal' person might rate their pain level as a 4 or 5 on a scale of 10, someone with depression/anxiety issues can oftentimes call it an 8.

Since refills are often prescribed by a primary care physician, the intended use can create an ongoing habit that goes unchecked. The researchers are recommending that some sort of psychological examination accompany any Rx for opioid-based painkillers.

I came across the article on page A14 of today's SF Chronicle just before tossing it and chances are, the report has been conveyed online.

[Abdullah71601]

I try to interpret my 8 as a 4 or 5. Keeps me out of the doctors office.

[locutus49]

I have been on and off opioids for chronic pain and they do make you hypersensitive to pain over time. I know there is opioid abuse in the US, but it is reaching the level of hysteria. Like the sin of alcohol that led to prohibition.

[Chewbacca]

I give up.

I'm joining the Paul, Jocke padded room posse.

[TheVTCGuy]

Originally Posted by chewbacca

i give up.

I'm joining the paul, jocke padded room posse.

4!

[Valenciawatchrepair]

The problem with most drugs is they have become easy to get in terms of reason for subscribing them. Doctors like to "throw drugs" at people. Kinda the same way a mechanic would throw money or parts at cars. Instead of finding the problem and fixing it, they just treat the symptom. This turns this drugs into a very profitable business and of course it just snowballs.

I learned this after having problems with heartburn. I'm 33. Began having bad heartburn at night and could not lay in bed. Then one day it was painful to swallow anything, even water. Everyone recommended an antacid(treat the symptom). I decided to do some research before taking a "pill." Found out that my problem was not too much acid, but low acid and too many carbs in my diet. Cut carbs way down, changed other parts of my diet. A few days after this change ALL SYMPTOMS were gone. I lost about 10 pounds and have stayed there(clothes were getting tight leading up to problems). If I splurge on my carbs again, the symptoms return, but I quickly correct it. Drugs used=ZERO

[swils8610]

I've been prescribed opioids for kidney stone pain in the past. They are effective. For me they do kind of relax me and def take away the pain. Anything drug/alcohol can be abused or become addictive over time.


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[Runnin' Rebel]

CARA

Cara Therapeutics (CARA) Jumped 12.2 % today
and is ready to go ballistic

5.00 to 26.00 in a year -- here's your grail watch money. Bought at 5, profits out at 15 and still going

[RonSwanson]

Cara was beaten up pretty badly today, I researched it per your recommendation, and I have to tell you, previous gains are great, it the fundamentals are still poor, increasingly negative EPS is problematic for example. In short this is the type of stock that if your going to recommend to strangers and in public you need to warn this is a very speculative play, and one you need to watch every single day, set stoplosses for, and consider taking profits as they come.

This is fine with me, i have Day traded commodities, so I understand the game. I just wouldn't want the casual investor treating this speculative play as if it were a blue chip.

Fwiw aapl (apple, iPhone) has performed admirably over the last couple years without any of this FDA drama.

Originally Posted by Runnin' Rebel

CARA

Cara Therapeutics (CARA) Jumped 12.2 % today
and is ready to go ballistic

5.00 to 26.00 in a year -- here's your grail watch money. Bought at 5, profits out at 15 and still going

[Runnin' Rebel]

Originally Posted by RonSwanson

Cara was beaten up pretty badly today, I researched it per your recommendation, and I have to tell you, previous gains are great, it the fundamentals are still poor, increasingly negative EPS is problematic for example. In short this is the type of stock that if your going to recommend to strangers and in public you need to warn this is a very speculative play, and one you need to watch every single day, set stoplosses for, and consider taking profits as they come.

This is fine with me, i have Day traded commodities, so I understand the game. I just wouldn't want the casual investor treating this speculative play as if it were a blue chip.

Fwiw aapl (apple, iPhone) has performed admirably over the last couple years without any of this FDA drama.

Really.. go to the stock thread see post 500... and post 516

No one on here is just going to dump a bunch of money on a stock with out looking deep..

[SearChart]

Opoids for depression/anxiety??! You only get opium based medicine here when you are screaming out in pain.

[BristolCavendish]

Originally Posted by SearChart

Opoids for depression/anxiety??! You only get opium based medicine here when you are screaming out in pain.

You misread the opening thread Bas. It pertains to those with depression/anxiety issues being prescribed opioids for pain management. According to the researchers, someone with a depression/anxiety disorder might have a lower pain threshold based on their mental state and interpretation of the actual pain. This can lead to a potential addiction as opioids in addition to being painkillers also provide a tranquilizing effect as well.

As aforementioned, the study recommends that physicians conduct some sort of psychological evaluation prior to prescribing or extending prescriptions for opioids.

[SearChart]

Originally Posted by BristolCavendish

You misread the opening thread Bas. It pertains to those with depression/anxiety issues being prescribed opioids for pain management.

Right, I see.

There should be some kind of screening before those are prescribed then, you can't prevent all addictions but I'm sure the number of addicted people can be lowered significantly.

[Muzz]

Every Doctor I know will screen against this. None of my buddies hand out those scrippies easy.

[Rock]

At one stage in my working life I was a 'Disability Counsellor' for the government Social Security system. I don't think I saw anyone with severe chronic pain who wasn't depressed. I've had very temporary severe pain and I was certainly depressed.
I think you could say that they were all "addicted" to various sorts of pain medication.
When I had temporary severe pain I would 'hang-out' for my next dose.
Until we can stick a set of sensors on someone's head and get a standardised, objective measure of how much pain they are feeling, assessment of someone else's pain is a pretty inexact science.
I'm not sure trying to use Psychs as a check on MDs would be very productive. The answer is responsible MDs not more layers of bureaucracy.

[MonBK]

While we are on the subject.

When I wake up in the afternoon with a hangover I usually take 2 Advil and a Bloody Mary.

If that doesn't help I take another Bloody Mary and a 3rd. if needed.

My serious question is, do you think I could be addicted to Advil?

[SearChart]

Originally Posted by MonBK

While we are on the subject.

When I wake up in the afternoon with a hangover I usually take 2 Advil and a Bloody Mary.

If that doesn't help I take another Bloody Mary and a 3rd. if needed.

My serious question is, do you think I could be addicted to Advil?

You're addicted to tomato juice, which is a healthy drink

[MonBK]

Originally Posted by SearChart

You're addicted to tomato juice, which is a healthy drink

That's good to know.

[de66]

Originally Posted by MonBK

While we are on the subject.

When I wake up in the afternoon with a hangover I usually take 2 Advil and a Bloody Mary.

If that doesn't help I take another Bloody Mary and a 3rd. if needed.

My serious question is, do you think I could be addicted to Advil?

Try to stop drinking, at least before getting to the hangover stage
If you still need advil then the answer would probably be yes
Cheers!

[Abdullah71601]

Originally Posted by MonBK

While we are on the subject.

When I wake up in the afternoon with a hangover I usually take 2 Advil and a Bloody Mary.

If that doesn't help I take another Bloody Mary and a 3rd. if needed.

My serious question is, do you think I could be addicted to Advil?

That much Advil can't be good for you.

[MonBK]

Originally Posted by de66

Try to stop drinking, at least before getting to the hangover stage
If you still need advil then the answer would probably be yes
Cheers!

Originally Posted by Abdullah71601

That much Advil can't be good for you.

Thanks guys, I'll stop the Advil.

[Canefan1]

^^

[axjimenez]

Originally Posted by MonBK

Thanks guys, I'll stop the Advil.

[mailman]

Originally Posted by MonBK

Thanks guys, I'll stop the Advil.

Take the Advil before you go to bed. You won't wake up with a hangover

[lapince]

Originally Posted by SearChart

Opoids for depression/anxiety??! You only get opium based medicine here when you are screaming out in pain.

Before yes, I broke my knee in 9 pieces, had 6 very large screws and a huge metal plate going through the top part of the tibia which was whole, and attched beneath the broken parts, excruciating pain, so much that I didn't sleep for 6 days, on the 6th day I yelled like a mad man for them to give me something, and they just filled me up with things to calm down and sleeping pills, was in gas still in pain, but the real pain seemed to have a hard time reaching the brain... to be continued...

Originally Posted by Muzz

Every Doctor I know will screen against this. None of my buddies hand out those scrippies easy.

Continued... but the last 10 years I twice got a nerve stuck or compressed in the spine, which lead each time to huge pains, first time in the leg, second in the arm and shoulder, second time was way worse than first, same as the operation, pain was 24/7, maybe a little less painful but not far behind, each time after 10 days of horrible pain, I was given morphine sulfate, works great on the pain, only problem is that taking it for 3 and 4 months, I had to continue 3 months more and slowly decrease to get to zero, but since 20 years in France they declared one of their goals, to stop or lower a patient's pain to tolerable levels, before that they gave opiates almost only to people with cancer or other thibgs of the sort

Originally Posted by Abdullah71601

That much Advil can't be good for you.

Exactly, a girlfriend's mother in Odessa had 3 drug stores, she knew I liked to party and asked me what I was taking for the hangover, I told her the usual things against headaches and pain, she told me it was very dangerous, for many different reasons, gave me tablets made from plants, but they were so big and hard to swallow, plus headache stayed for 2 hours instead, that I quickly went back to Advil and co...

[BristolCavendish]

Originally Posted by MonBK

Thanks guys, I'll stop the Advil.

Since 2 Advils (ibuprofen) /400 mg every 6 hours is the maximum recommended dosage, you're probably OK (as long as it isn't habitual). If an individual has any gastrointestinal issues, the extended use of Advil can sometimes exacerbate stomach bleeding which is why most ulcer patients aren't prescribed it. On the other hand, the extended use of Tylenol (acetaminophen) can lead to liver damage. Most pharmaceutical opioids like Vicodin are usually a blend of opioid and acetaminophen (i.e. 5-10 mg Vicodin + 300-400 mg Tylenol thus anyone trying to 'max-out' or trip on the opioid content is also ingesting far too much acetaminophen in the process.

Originally Posted by lapince

...I quickly went back to Advil and co...

Advil is also my go-to temporary painkiller as it 'localizes' the source of pain rather than numbing receptors in the brain. I've tried/used Vicodin (5/300) but it doesn't seem to work as well.

Individual physiologies and brain chemistries respond differently which makes any Rx a tricky one at best.

[Moggo]

Originally Posted by Rock

At one stage in my working life I was a 'Disability Counsellor' for the government Social Security system. I don't think I saw anyone with severe chronic pain who wasn't depressed. I've had very temporary severe pain and I was certainly depressed.
I think you could say that they were all "addicted" to various sorts of pain medication.
When I had temporary severe pain I would 'hang-out' for my next dose.
Until we can stick a set of sensors on someone's head and get a standardised, objective measure of how much pain they are feeling, assessment of someone else's pain is a pretty inexact science.
I'm not sure trying to use Psychs as a check on MDs would be very productive. The answer is responsible MDs not more layers of bureaucracy.

Most Psychs have bigger problems than the patients. I've met more than a few who self prescribe!


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[Thatguy]

Most people with mental disorders are more prone to addiction anyway. Can be alcohol, nicotine or opioids. It's a way of self medicating.


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[hugs]

Interesting. I would have assumed people with mental disorders would be less prone to pain as they have other things going on in their mind. Someone with a clear head could concentrate more on being in pain..

[SearChart]

Ibuprofen is quite bad for the cardiovascular system, I wouldn't use it that much. Let alone use it with alcohol.